CAIRN OptoTIRF V2
Compact and powerful, yet inexpensive, stepper-motor-controlled TIRF
The OptoTIRF V2 is a stepper-motor-controlled TIRF illuminator suitable for any research-grade inverted microscope. It focuses a single or multimode laser spot anywhere in an objective lens' back-aperture using joystick or software control, and stores and recalls preset positions through digital or COM interface. It's appropriate for TIRF and oblique illumination at a range of penetration depths and wavelengths. The 360 degree stepper-motor-control allows the user to illuminate from multiple points throughout an experiment, making it easy to modify the illumination and minimize fringes or shading gradients. A dither function improves field homogeneity by reducing point TIRF artifacts. A motorized bypass port allows for widefield illumination with LEDs or a liquid light guide, or the attachment of a second TIRF module for simultaneous dual-color imaging.
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Easy to set up, align, and run
Works with single-mode and multi-mode lasers
Motorized movement of the illumination spot
Joystick or software control
APPLICATIONS
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Single molecule localisation & tracking
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Kinetic studies of single molecule interactions (i.e. ligand binding, protein: protein and protein: DNA interactions)
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Kinetic studies of proteins (i.e. actin filaments & microtubules)
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Super-resolution techniques (i.e. PALM/STORM) ) for subdiffraction localization of single molecules
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Low-cost, open source EasySTORM
KEY BENEFITS
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Compact modular system for easy integration with other modalities onto any inverted microscope base
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Motorized movement of illumination spot for optimized point TIRF / oblique illumination
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Joystick or software control –simple COM commands or digital control will work with any imaging software
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Motorized widefield bypass mode
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Accommodates singlemode or (small) multimode fiber input for use with Cairn or third-party laser sources
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Integrated variable field stop with X_Y alignment
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Simple optical path suitable for adaptation for custom requirements
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Affordable upgrade for existing frames or laser sources
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Modular collimator allows quick and easy optimisation for field flatness or power density
HIGH END IMAGING
AT AN AFFORDABLE
PRICE
Confocal/Super Resolution/TIRF Packages Available using industry-leading products
Voxyl Offers a variety of confocal systems. These systems are configured based on your exact needs and budget. Please contact Voxyl for more information on our current confocal and TIRF systems
