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Crest Optics DeepSIM

Super resolution microscopy that answers the deep biological questions effortlessly

For the advancement of science, we at CrestOptics think that super-resolution should be available to scientists everywhere. DeepSIM is the first super-resolution module designed to work with any existing upright or inverted microscope that has a camera connection. A confocal microscope-like interface makes it simple for scientists to gather detailed information from biological samples.

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Confocal Upgrade

Stand-Alone Super Resolution

Deep Imaging

~100nm Resolution in XY

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DESCRIPTION

Reliable, Simple to Use and Affordable Solution 

Based on a multi-spot structured illumination system, the DeepSIM is a reliable, simple to use and affordable solution to study cellular structures up to an XY resolution of ~100nm.

 

Super-resolved optical sectioning, with Z resolution up to ~ 300nm, can be obtained using both high (60X – 100X) and low magnification (20x – 40x) objectives to expand the range of applications to include complex 3D models such as tissues, organoids, spheroids and small organisms.

DEEPER
IMAGING

Super-Resolved Data Over 50µm Z in Depth

 

The DeepSIM is designed to work with samples of thicknesses comparable to those used in confocal microscopy, giving super-resolved data over 50µm Z in depth in non-clarified samples.

This means that more meaningful data can be obtained from native heterogeneous complex samples using routine preparation protocols.

DeepSIM enables the effortless study of live-cell dynamics through a temporal resolution greater than 10fps (1024×1024 px FOV), allowing biological changes to be tracked at cellular and subcellular levels.

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What You Can See

How You See

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20X

WIDEFIELD

CONFOCAL

DeepSIM SUPER RESOLUTION

EVOLUTION THROUGH COMPATIBILITY

DeepSIM is designed to be a truly enabling technology where performance is combined with the flexibility of a modular, expandable system available either as Super Resolution add-on module for CrestOptics X-light V3 Spinning Disk system or standalone equipment.

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Combination with spinnign-disk confocal

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Stand-Alone Unit

TECHNICAL SPECIFICATIONS

  • FOV: 1024x1024pixel (66x66µm 100X | 333x333µm 20X)

  • Laser: Spectral range: excitation: 400-750 nm; emission: 400-850 nm

  • Camera: Compatible with any triggerable camera having 6.5 µm pixel size

  • Dual camera option: Available

  • Acquisition speed: 13fps (1024x1024px)

  • Spinning disk upgrade: Compatible with CrestOptics X-light V3​

  • Objectives compatible: From 100X to 20X range

  • Resolution: Lateral Resolution (FWHM): ~100 nm (100X NA 1.45) Axial Resolution (FWHM): ~300 nm (100X NA 1.45)

  • Software: Micro-Manager / VisiView® / NIS elements

  • Recommended Installation Conditions: Temperature 23 ± 5˚C, Humidity 70% RH or less (no condensation)

  • Weight: 44 lbs | 20Kg
     

  • Dimensions: 14.0 (w) x 17.1 (L) x 11.8 (h) inches | 356.0 (w) x 435.0 (L) x 300.0 (h) mm

HIGH END IMAGING

AT AN AFFORDABLE

PRICE

Confocal/Super Resolution/TIRF Packages Available using industry-leading products 

Voxyl Offers a variety of confocal systems. These systems are configured based on your exact needs and budget.  Please contact Voxyl for more information on our current confocal and TIRF systems

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CREST OPTICS DeepSIM DOWNLOADS

CREST OPTICS DeepSIM BROCHURE

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